LPL and hypertriglyceridemia: Higher doses of intravenous propofol (lipid emulsion) can result in hypertriglyceridemia as lipoprotein lipase becomes saturated at a serum triglyceride concentration of ~300 to 400 mg/dL resulting in non-enzymatic means of elimination (e.g., from first order kinetics to zero order kinetics) with the lipid emulsion and its remnants being eliminated via the reticuloendothelial system [21].