POU5F1 and anaplastic large cell lymphoma: Since the SORE6 reporter was originally designed to detect the transcription activity of Sox2 and Oct4, two of the four originally described iPS factors, we examined the protein expression of these two proteins in a cohort of five ALK + ALCL cell lines including SupM2, Karpas 299, UCONN-L2, SU-DHL-1, and SR2.