In a study of ventricular arrhythmias in children, Mazurek et al. [35] found that the level of NT-proBNP increased with the severity of the ventricular arrhythmia, and the determination of NT-proBNP is helpful for the diagnosis and grading of ventricular arrhythmias. This evidence concerns the gene NPPB and Ventricular arrhythmia.