Seki reported that the fake receptor of transforming growth factor-beta (TGF-β), bone morphogenetic protein, and activin membrane-bound inhibitor (BAMBI) could be downregulated by stimulating the TLR4 on the membrane of hepatic stellate cells, which further activates the TGF-β1 signal pathway and contributes to the liver fibrosis [19]. Here, TGFB1 is linked to Hepatic fibrosis.