Lazzarotto, et al. [4] found that the incidence of fetal or newborn congenital CMV infections was very similar in both pregnant women with positive IgM antibody and low IgG avidity and those with antibody seroconversion (25.0% in women who were IgM positive with low IgG avidity and 30.3% in women with antibody seroconversion). Here, CD40LG is linked to cytomegalovirus infection.