CTU2 and lung cancer: In addition, two of the 187 proteins significantly correlated with METTL1 protein expression, CTU2 (cytosolic thiouridylase subunit 2) and XPOT (exportin for tRNA), also exhibited significant positive correlation with the METTL1 CRISPR/Cas9 CERES score in CCLE lung cancer cell lines (Fig. 5D).