In contrast, when TGFβ signaling was selectively inhibited in experimental fibrosis using the TβRI inhibitor SD-208, the induction of autophagy in bleomycin-induced fibrosis was abrogated and the levels of BECLIN1, ATG7 and p62 were comparable to those of non-fibrotic controls (Supplementary Fig. 5). The gene discussed is ATG7; the disease is fibrosis.