Four genes, CHAC1 (HR = 0.808, P = 0.021), GGT5 (HR = 1.256, P = 0.007), GPX8 (HR = 1.349, P = 0.002), and PXDN (HR = 1.315, P = 0.004), were correlated with GC patients overall survival significantly. Here, CHAC1 is linked to gastric cancer.