As shown in Fig. 9a, “p53 signaling pathway”, “cell cycle”, “DNA replication”, “mismatch repair” and “RNA degradation” were enriched in high-risk samples, while a variety of immune-related pathways including “B cell receptor signaling pathway”, “T cell receptor signaling pathway”, “acute myeloid leukaemia”, “FcγR mediated phagocytosis”, “FcεRI signaling pathway”, and “primary immunodeficiency” were enriched in the low-risk group. The gene discussed is TP53; the disease is acute myeloid leukemia.