In addition, the infiltration of CD4+CD39+ T cells tended to decrease (normal versus tumor = 14.43% ± 12.67% versus 7.01% ± 8.73%; P = 0.22; Figure 1, A and C) and the frequency of CD8+CD39+ T cells (normal versus tumor = 8.60% ± 4.58% versus 12.02% ± 12.92%, P = 0.67; Figure 1, A and D) tended to increase in RSCRC. The gene discussed is CD4; the disease is neoplasm.