Obesity induces a profound metabolic rewiring in EAT, with downregulation of genes associated with glucose metabolism (e.g., SLC24A, CS, GPT, OGDH, ACO2, GPI, LDHD) and lipid metabolism (e.g., GYS2, GPAT3, CRAT, FASN, ACADVL, DGAT1, DGAT2, NAT8L, SCD) as well as changes in genes related to adipogenesis (HES1, MXD3, NR4A2, RGS2, PPP1R15B, ADAMTS1, CEBPD, KDM7A). Here, FASN is linked to Obesity.