In addition, EVs containing proteins related to mitochondrial dynamics, including mitochondrial fission protein 1 (FIS-1), and mitochondrial dynamin-like GTPase 1 (OPA-1) were found to induce, together with FAO, mitochondrial redistribution to the edge of melanoma cells, favoring migration and consequently melanoma aggressiveness [45]. Here, FIS1 is linked to melanoma.