CD68 and Krabbe disease: Indeed, the contribution of microglia to the pathology of these leukodystrophies is supported by findings in patient postmortem brain tissue, in which CD68+ phagocytic microglia are abundant in both the affected and least-affected white matter of Krabbe disease (Del Bigio, 2018), MLD and X-ALD patient brain tissue (Bergner et al., 2019).