MYC and B-cell non-Hodgkin lymphoma: Hilton et al. subsequently described a collection of DHITsig-positive tumors lacking DH/TH cytogenetics by breakapart FISH, but in which cryptic MYC or BCL2 rearrangements were detectable by whole-genome sequencing, thus making them true high-grade B-cell lymphomas with MYC and BCL2 rearrangements.