CD40LG and neoplasm: To test the antitumoral effects of Ad-CD40L-DC alone, animals were injected with 106 Ad-CD40L-DC i.p. As shown in Figure 3a middle/right, a significant reduction of tumor-growth was documented (315+/−194 mm3) compared to Ad-LacZ-DC (682 ± 200 mm3) (p = 0.009) at day 19.