CD40LG and neoplasm: Interestingly, we detected significant increase of subG1-fraction in Hepa129-mAFP- and Hepa1–6-cells (Figure 7a) after culturing with the supernatants from Ad-CD40L-DC (p < 0.01), (Figure 7b,c), indicating induction of tumor cell apoptosis by Ad-CD40L-DC.