In order to investigate the functional consequences of stromal JUNB loss on distant metastasis, EO771.LMB breast cancer cells tagged with a mCherry reporter [28] were orthotopically injected into the mammary fat pad of Junb KO and CTR mice and metastasis was analyzed after surgical removal of the primary tumor (Fig. 2a). The gene discussed is JUNB; the disease is breast carcinoma.