PDCD1LG2 and neoplasm: While it is clear that DCs provide a critical link between innate and adaptive immune responses within the tumor microenvironment and draining lymph nodes [59–61], it is worth noting that, as with other myeloid cells within the tumor microenvironment, activated conventional DCs express PDL1 and PDL2, which serve as ligands for the PD1 checkpoint molecule [62].