APC and hereditary cancer: Identified cases involved 5 different hereditary cancer genes; the most common being TP53. Of the 24 patients in our cohort, 17 (70%) had findings in TP53, 2 (8.3%) in CHEK2, 3 (12.5%) in ATM, 2 (8.3%) in APC and 2 (8.3%) in BRCA1. Two out of twenty-four (8.3%) patients had pathogenic variants in more than one gene.