Compared with non-severe patients, the levels of several infection-related biomarkers were significantly higher in severe or critical patients, including procalcitonin, cardiac troponin I (cTnI), N-terminal prohormone of brain natriuretic peptide (NT-proBNP), C-reactive protein (CRP) (all P < 0.001). This evidence concerns the gene TNNI3 and infection.