The areas under ROC curves (AUROCs) were 0.868 for NLR, 0.811 for IL-6, 0.802 for IL-2R, 0.763 for IL-8, 0.731 for IL-10 and 0.699 for TNF-α when performing prediction of severe or critical COVID-19 cases (Figure 3A). This evidence concerns the gene CXCL8 and COVID-19.