Besides, previous studies demonstrated that interleukin-2R (IL-2R)/lymphocyte, interleukin-6 (IL-6) and interleukin-10 (IL-10) might be the potential biomarkers for early diagnosis and indicators for higher risk of disease deterioration when predicting the disease progression of COVID-19 [3, 4, 14]. This evidence concerns the gene IL2RA and COVID-19.