In our study, we discovered that WDR4 expression levels were correlated with the expression levels of CD276 in ESCA, ACC, BRCA, GBM, OV, KIRC, HNSC, KIRP, LIHC, LGG, LUAD, PCPG, STAD, PRAD, SARC, THCA, UVM, and UCEC, suggesting that WDR4 may regulate the immune response in these tumour types. The gene discussed is CD276; the disease is glioblastoma.