TGFB1 and lung cancer: Further analysis revealed that circPTK2 (hsa_circ_0008305) could suppress TGF-β-induced EMT and metastasis through the regulation of TIF1γ in NSCLC [82], presenting a novel mechanism by which circRNA modulates TGF-β-induced EMT and lung cancer metastasis, and suggesting that targeted overexpression of circPTK2 could provide a therapeutic strategy for advanced NSCLC.