Scoliosis (Fig. 2b) occurred in 40.5% (45/111) of LAMA2-CMD at median age of 6.0 years (range 0.5–12.0 years), and lordosis occurred in 8.1% (9/111) of LAMA2-CMD at median age of 3.0 years (range 2.0–7.0 years). The gene discussed is LAMA2; the disease is scoliosis.