GSEA indicated that the significantly enriched gene sets in the high-risk subgroup with poor survival were some crucial signaling pathways and cellular processes, including ubiquitin mediated proteolysis, Wnt signaling pathway, mTOR signaling pathway, TGF-β signaling pathway, pathways in cancer, MAPK signaling pathway, RNA degradation, and cell cycle. This evidence concerns the gene TGFB1 and cancer.