METTL3 and thyroid gland carcinoma: We observed that the expression level of 11 m6A RNA methylation regulators (METTL3, METTL14, RBM15, WTAP, YTHDC1, YTHDC2, YTHDF1, KIAA1429, FTO, ZC3H13 and ALKBH5) was significantly decreased in thyroid carcinoma tissues compared to those in normal thyroid tissues, whereas the expression level of HNRNPC was increased in thyroid carcinoma tissues (Fig. 1B).