CD8A and neoplasm: In the KIRC cohort, we found that 9 out of 16 immune cells had significantly higher infiltration enrichment scores in the high-risk group: CD8+ T cells, macrophages, plasmacytoid dendritic cells (pDCs), T helper cells, follicular helper T cell (Tfh), helper T cells 1 (Th1 cells), helper T cells 2 (Th2 cells), tumour infiltrating lymphocyte (TIL) and regulatory T cell (Treg), while immature dendritic cells (iDCs) and mast cells showed the opposite pattern (Fig. 10A).