The anti-proliferative effect of EZH2 inhibitor EPZ011989–8 and pan-HDAC inhibitors vorinostat, panobinostat (hydroxamates), and mocetinostat (benzamide) were screened using live cell imaging (IncuCyte ZOOM®) and/or MTS in VAESBJ and GRU1 epithelioid sarcoma and A204 rhabdoid tumor cell lines (Fig. 1A). The gene discussed is EZH2; the disease is epithelioid sarcoma.