DDX11 and neoplasm: We first analyzed the expression of lncRNA DDX11-AS1 in ESCA tissues and cell lines, and found that the expression of lncRNA DDX11-AS1 in ESCA tissues and cell lines was significantly increased, and lncRNA DDX11-AS1 also predicted a poor prognosis, so we speculated that lncRNA DDX11-AS1 was a tumor-promoting factor in regulating the progression of ESCA.