Moreover, the results of the correlation analysis showed that the levels of REV7 and REV3L were positively correlated in glioma tissues (Figure 1c, r = 0.29, p = 0.00015); furthermore, the mRNA and protein expression of REV7 in glioma tissues were determined by the qRT-PCR and western blot methods, respectively. This evidence concerns the gene MAD2L2 and central nervous system cancer.