Severe EBV infection is also associated with deficiency of the MAGT1 transporter, GATA2, the interleukin-2 (IL-2)-inducible T-cell kinase, the RAS guanyl-releasing protein 1 RASGRP1, CD27, CD70, and 4-1BB (6, 7, 9, –, 13). This evidence concerns the gene RASGRP1 and Epstein-Barr virus infection.