Patients with hyperandrogenism+oligo/anovulation+polycystic ovaries (PCO) or hyperandrogenism+PCO had lower total ApoE-containing and ApoE-poor HDL-PAF-AH activities, while those with oligo/anovulation+PCO showed decreased total and ApoE-poor HDL-PAF-AH activities, compared to the control women. The gene discussed is APOE; the disease is hyperandrogenism.