Furthermore, Dock10.1 isoform regulates T cell activities, while Dock10.2 isoform regulates CD23 expression on B cells, sustains B cell lymphopoiesis in secondary tissues, and up-regulates the IL4>Stat6 pathway [62], an essential pathway for SS development in C57BL/6.NOD-Aec1Aec2 mice [17]. Here, IL4 is linked to synovial sarcoma.