has also been associated with inflammatory disorders, such as rheumatoid arthritis and metabolic diseases [25,44,45,46], where it could play a role in sustaining inflammatory tone through the stimulation of TH17 and CD8+ T cells-derived pro-inflammatory cytokines (i.e., IFN-γ and TNF-α) [47,48,49]. The gene discussed is IFNG; the disease is rheumatoid arthritis.