In addition to the upregulation of pro-inflammatory signals, several inhibitory markers, such as Pd-l1 (Pdcd1lg1), and Pd-l2 (Pdcd1lg2) were identified as key molecules, particularly at one day p.i. PD-L1 is expressed by a large range of cell types, including tumor cells, macrophages, monocyte-derived myeloid dendritic cells (DCs), epithelial cells, T cells, and B cells. The gene discussed is CD274; the disease is neoplasm.