RUNX1 and acute lymphoblastic leukemia: Other frequently deregulated miRNAs in ALL are miR-100, miR-125b, miR-99a, miR-126, and let-7c that are overexpressed in ETV6-RUNX1 patients [122,123], whereas miR-181a was found as markedly downregulated in this subtype of ALL [124,125] (Table 1).