Key molecules that contribute to PA augmentation of COVID-19 pathologies included PTGS2; cytokines, such as IL1β, IL6, and IFNB1; chemokines, such as CCL2, CCL5, and CXCL8; translation regulators, such as EEF1A; transcription factors, such as FOS and NFκB; and molecules involved in apoptosis, such as BAX. The gene discussed is CXCL8; the disease is COVID-19.