Per SD increase in genetically-predicted IL-6 levels, the OR for schizophrenia was: IVW OR=1.24 (95% C.I., 1.04-1.47) using the Swerdlow et al instrument; and Wald Ratio OR=1.10 (95% C.I., 1.03-1.17) using the Sarwar et al instrument. This evidence concerns the gene IL6 and schizophrenia.