In contrast, ENCODE RNA-seq data showed that HOXA-AS3 and HOXB-AS3 are well expressed in HT-29 (S6 Fig)–a human colon adenocarcinoma cell line that under certain growth conditions exhibits characteristics of mature intestinal cells, such as enterocytes or mucus producing cells which have brush borders and expresses Villin and additional intestinal microvilli proteins [28,29]. The gene discussed is HOXB-AS3; the disease is colon adenocarcinoma.