CDC42 and lung cancer: As an antimetastatic drug in lung cancer, TBD concentrations of 0.5–5 μM attenuated the migration and invasion of H292 cells and suppressed the activation of AKT and its downstream signaling, such as focal adhesion kinase (FAK), cell division control protein 42 homolog (CDC42), integrins and EMT markers, including snail and vimentin [209,210].