EGFR and colorectal cancer: For these kinases, the epidermal growth factor receptor (EGFR) is the most important target for breast and lung cancer treatments, but it is also an attractive target for numerous other types of cancer (e.g., esophageal squamous cell carcinoma [4], colorectal cancer [5], head and neck squamous cell carcinoma [6], nasopharyngeal cancer [7], glioblastoma [8], and pancreatic cancer [9]).