THBS4 and disease of the tendon: Targeting Krüppel-like factor 6 (KLF6), miR-148a-3p could affect the expression of TSP-4 in tendonocytes, and is closely related with Tsp-4 levels in tendinopathy tissues, which also promoted endothelial cell (EC) angiogenesis (Ge et al., 2018).