Hu et al. (2020) reported that circMTO1 had a negative effect on the expression of miR-3200-5p by sponging it. Moreover, circMTO1 was confirmed to compete with phosphatidylethanolamine binding protein 1 (PEBP1) for binding to miR-3200-5p to decelerate the progression of GC (Hu et al., 2020). Furthermore, Song et al. (2020) also found that circMTO1 might serve as a ceRNA that binds to miR-199a-3p, thereby increasing the expression of PRKC apoptosis WT1 Regulator (PAWR), and ultimately effectively inhibiting GC progression. The gene discussed is WT1; the disease is gastric cancer.