MUC1 and breast carcinoma: Li and colleagues detected MUC-1 positive human breast carcinoma MCF-7 cells using specific interaction between MUC-1 and its aptamer, covalently conjugated to the surface of GNRs by Au-thiolate chemistry and scan the signals with unique localized surface plasmon resonance (LSPR) spectra (Li et al., 2016a) (Figure 4A).