INS and obesity due to melanocortin 4 receptor deficiency: A total of 413 participants from the baseline population of the FiLWHEL study were included in the analysis, with variation regarding the major outcomes; 413 participants were included for general obesity (no. of cases = 124), 411 participants were included for abdominal obesity (no. of cases = 177), and 405 participants were included in the dyslipidemia and insulin resistance analyses (no. of cases = 39 for TG, 28 for HDL, 76 for LDL, 109 for TC, 43 for TG/HDL, 141 for HbA1c, 43 for FBG, 57 for insulin levels, and 65 for HOMA-IR).