MK-2206 (Akt inhibitor), rapamycin (mTORC1 inhibitor), Torin-1 (mTORC1&2 inhibitor), and PX-478 (HIF-1α inhibitor), significantly downregulates viral transcripts in SARS-CoV-2 infected Huh7 cell culture, indicating they could be repurposed and potentially used to treat COVID-19 (60). The gene discussed is HIF1A; the disease is COVID-19.