Univariate analyses revealed that the baseline bone marrow tumor burden, CRS severity, several serum biomarkers (including max lg CRP, IL-10, IFNγ, ferritin, and D-dimer levels), and the usage of tocilizumab/corticosteroids were statistically associated with the incidence of severe cytopenia (Supplementary Tables 3–5). Here, CRP is linked to congenital rubella syndrome.