Previous studies have established that LINC00665 acts as an oncogenic molecule in multiple human cancers, such as breast cancer (10), gastric cancer (11), hepatocellular carcinoma (12), prostate cancer (13), osteosarcoma (14), colorectal cancer (15), myeloma (16), glioma (17), ovarian cancer (18), and NSCLC (19). This evidence concerns the gene LINC00665 and hepatocellular carcinoma.