Interestingly, overall survival (OS) of patients with bladder cancer with high FN1 expression was significantly lower than that with low expression (P = 0.012), while the OS of bladder cancer patients with low RPL22L1 expression was significantly lower than that of patients with high expression (P = 0.034) (Figure 7A). The gene discussed is RPL22L1; the disease is urinary bladder carcinoma.