Some pathways such as P53, IL6/JAK/STAT3, TNFα, and IL2/STAT5 have been proven to be related to AML or other tumors (Rucker et al., 2012; Binder et al., 2018; Ni et al., 2020; Wang et al., 2020). This evidence concerns the gene TP53 and acute myeloid leukemia.