ADAMTS13 and cardiovascular disorder: However, epidemiologic evidence shows conflicting results on the association between ADAMTS13 level and activity and the risk of cardiovascular diseases such as myocardial infarction (MI), angina pectoris, and stroke (Danesh et al., 2004; Crawley et al., 2008; Horii et al., 2008; Peyvandi et al., 2010; Wieberdink et al., 2010; Hanson et al., 2011).