Based on the inverse-variance weighted (IVW) analysis results, the ADAMTS13 level was not causally associated with CHD (b = −0.001, se = 0.001, p > 0.05), MI (b = −0.001, se = 0.001, p > 0.05), AF (b = 0.00003, se < 0.001, p > 0.05), HF (b = −0.00003, se < 0.001, p > 0.05), and VTE (b = −0.00003, se < 0.001, p > 0.05). This evidence concerns the gene ADAMTS13 and coronary artery disorder.