In China, GJB2 c.[235delC] + [235delC] homozygotes were the most common, which accounted for 55.10% of GJB2 gene-related deafness, followed by 235delC heterozygote (20.40%), and 235delC/299-300delAT compound heterozygote (10.2%) (Zheng et al., 2000). The gene discussed is GJB2; the disease is deafness.