KO of the gene encoding ficolin-A (homologue of human ficolin-2 and/or 3) decreased the survival of mice given one million CFU H37Rv strain i.v. compared to WT, but survival was enhanced compared to WT when KO mice were given a plasmid containing ficolin-A or ficolin-2 by i.m. electroporation on the day of infection (73). The gene discussed is FCN1; the disease is infection.